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Moreover, Cys26 from the N-terminal segment and Cys584 from the IPT1 domain are closely adjacent to each other in our model, suggesting that they form a disulfide bond to further strengthen the interaction between these two structural motifs (Supplementary Fig

R., Medici, L

Zhou X, Li C, Xu W, Chen J

At specified time intervals (0 h, 1 h, 2 h, 4 h, 6 h, 8 h, 12 h, 24 h, 48 h), the sample solution (1.5 mL) was withdrawn from the dialysate, after which an equal volume of fresh corresponding solution (1.5 mL) was promptly added back into the dialysate to maintain the overall volume